Advances in Mechanical Analysis: Probing Viscoelasticity at the Nanoscale

This technical note discusses the advancements in viscoelastic characterization at the nanoscale using Atomic Force Microscopy. Traditional AFM methods have limitations when characterizing materials that do not possess a regular atomic lattice, such as polymers and biological tissues, due to their complex, viscous behavior. To address this, Nanosurf has developed an advanced module that allows for oscillatory probing using a cantilever to determine both viscous and elastic responses at a local scale with high temporal resolution. This method enhances understanding of material behaviors under various conditions, especially in the high-frequency range, which is crucial for materials where viscoelastic properties significantly impact their functionality and performance.

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Learning Objectives

  1. Understand Viscoelasticity: Gain knowledge about the nature of viscoelastic materials, which exhibit both viscous and elastic characteristics, and how these properties affect their mechanical response
  2. Learn AFM Techniques for Viscoelasticity: Learn about the application of AFM in measuring viscoelastic properties using oscillatory probing, which involves indenting or compressing a sample with a cantilever and observing the resulting force response.
  3. Explore High-Frequency Measurements: Understand the significance of high-frequency measurements in viscoelastic characterization, particularly using Nanosurf's CleanDrive technology, which allows for precise measurements at frequencies up to 40 kHz, even in liquid environments.
  4. Application Insights: Comprehend how these measurements are critical in assessing material performance in practical applications like extrusion or molding and in understanding the micro- or nano-structure of complex materials such as polymers and biological cells.
  5. Examine Practical Case Studies: Learn through case studies, such as the analysis of HeLa cells, how high-frequency viscoelastic properties can provide insights into cellular mechanics and potentially lead to new therapeutic approaches.
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