How to measure mechanics of single cells
06.11.2024
The ultimate tool for nanoscale research from biological molecules to advanced new materials.
The versatile mid-range research AFM that grows with your demands in modes and accessories.
A compact affordable research AFM that is astoundingly easy to use, with more than 30 modes and options.
Measure roughness and other material properties of heavy and large samples up to 300 mm and 45 kg.
Bringing the power of DriveAFM to a wafer metrology system purpose-built for the requirements of the semiconductor industry.
For unique requirements, we will design a bespoke AFM solution, leveraging our decades of engineering expertise.
Slide an AFM onto your upright optical microscope turret for a leap in resolution.
One of the smallest ever AFMs, created for integration into custom stages or existing setups.
A flexibly mountable research-grade scan head for integration into custom stages or existing set ups.
What is atomic force microscopy (AFM)? How does AFM work? What AFM modes do I really need? How do I get started with AFM?
Learn how AFM works with cantilever/tip assembly interacting with the sample. Explore CleanDrive technology, calibration methods, and feedback principles for precise nanoscale imaging.
An overview of common AFM modes. To learn about each mode in more detail and see application, view the full article.
We regularly publish detailed reviews providing practical guidance and theoretical background on various AFM applications.
Read detailed technical descriptions about selected AFM techniques and learn how to perform specific measurements on Nanosurf instruments.
A library of links to research papers in which Nanosurf instruments were used.
Learn AFM from our library of recorded webinars, covering different measurement techniques, modes, and areas of application.
Short video clips explaining how to perform different operations on Nanosurf instruments.
Watch a product demonstration to learn about the capabilities of our AFMs.
Short videos of our AFMs.
Browse news articles, press releases and a variety of other articles all around Nanosurf.
Browse Héctor Corte-Léon's weekly experiments, for inspiration, entertainment, and to discover everyday applications of AFM.
The LlBio laboratory at the University of Lorraine in France is a distinguished research facility, celebrated for its depth of knowledge across various biological domains. It spearheads research, nurturing innovation and scientific progress both locally and on the global stage. With its multidisciplinary ethos and cutting-edge infrastructure, the laboratory remains a pivotal contributor to biological science.
Jennifer Burgain, an Associate Professor of food science at LlBio, faced a complex issue concerning food powders. These powders, made up of distinct particles, have surface characteristics that are integral to their functionality, especially in terms of flowability and reconstitution. The overarching aim was to develop food products that showcased peak functional attributes, prioritizing flowability and reconstitution. This emphasis is crucial since food powders, typically designed for extended storage, have a reduced water content, which curtails unwanted reactions such as bacterial proliferation and enzymatic activities. Yet, their efficacy can be influenced by temperature and humidity shifts during prolonged storage and global distribution.
The move to invest in an AFM stemmed from the dedication to meticulously characterize the surfaces of food powders, ensuring the delivery of products with unwavering and superior functional attributes, irrespective of environmental fluctuations. AFM has been instrumental in addressing these specialized challenges in food science. Dr. Burgain's prior engagements with AFM during her academic pursuits equipped her with the insight to discern its potential for the type of analysis required here. In her postdoctoral phase within an industry-led project, she had adeptly employed the AFM to scrutinize food powders, unearthing valuable insights into particle behaviors.
However, a certain ambiguity about the sample's nature had to be addressed before making the final decision to purchase an AFM. Given the relatively large dimensions of the food powders and their pronounced height variations compared to standard AFM samples, the quest was to pinpoint an AFM system that could adeptly analyze such samples without breaking the budget.
Dr. Burgain's introduction to Nanosurf was through a colleague's recommendation. Confronted with the unique challenge of analyzing the samples, Nanosurf emerged as the sole provider offering a top-tier solution with an impressive balance of cost and quality. Nanosurf's proactive engagement, coupled with their invaluable advice on AFM studies, set them apart. Their introduction of a pivotal feature—an environmental chamber for modulating temperature and humidity during experiments—was a cornerstone for food powder research. Engaging dialogues with Nanosurf and a hands-on demonstration at the LlBio laboratory solidified the choice: the Nanosurf FlexAFM. For LlBio, Nanosurf's offering was unparalleled, leading to the selection of the FlexAFM equipped with the environmental chamber.
This innovation has been transformative, with the LIBio team now pioneering the scanning of food powders with precise control over temperature and humidity. This capability allows them to monitor particle surface alterations in response to temperature or humidity changes. With Nanosurf’s FlexAFM, Dr. Burgain and her team have been able to decode larger-scale phenomena through measurements that were previously out of reach.
Dr. Burgain's initial experience with Nanosurf's AFM was positive. With her background in using another AFM, she found Nanosurf's FlexAFM to be more intuitive and user-centric. While there's an inherent learning curve with any AFM, the FlexAFM's learning trajectory is notably smoother.
Today, the FlexAFM remains a linchpin in LIBio's research arsenal, amplifying their investigative prowess and deepening their comprehension of food powders and associated phenomena. At its core, Nanosurf is a compact yet efficient entity, delivering steadfast and high-caliber equipment. Their service ethos is marked by agility and promptness, backed by a team of adept professionals offering unwavering technical and scientific support.
A defining moment was the exhilaration of capturing and detailing the dynamic evolution of food powders as they transitioned through the glass phase, a feat realized through the Nanosurf alliance.
In summary, the partnership with Nanosurf has bolstered the University of Lorraine's LlBio laboratory's research capabilities, paving the way for novel explorations and pioneering discoveries in food science and material characterization.
Find out more about Nanosurf's FlexAFM
06.11.2024
How to measure mechanics of single cells
05.08.2024
Exciting news as SPECS-TII Inc. integrates Nanosurf AG services in the US, enhancing their offerings in scanning probe ...
07.06.2024
Discover the exceptional researchers honored at the Swiss Nano Convention 2024 for their groundbreaking contributions ...
18.04.2024
FridayAFM: See how one of our Industrial AFMs can be used to look at the surface of mobile phones.
28.03.2024
Explore the fascinating world of AFM experiments with bismuth oxide layers in this detailed blog post. Learn about ...
21.03.2024
FridayAFM: Point contact diode on lead sulfide.
Interested in learning more? If you have any questions, please reach out to us, and speak to an AFM expert.